This is a summary list of all core laboratories at University of Texas at San Antonio . The list includes links to more detailed information, which may also be found using the eagle-i search app.
These laboratories are dedicated to 'Cellular and Tissue Engineering' research activities which focus on in vitro studies of mammalian cell and protein interactions with material substrates, biomaterials (including nanostructured ones), biocompatibility, and the effect of select biochemical and biophysical (specifically, sustained and cyclic pressure and electrical) stimuli on mammalian cell function pertinent to new tissue formation and regeneration.
The High Performance Computing Center/Computational Biology Initiative (HPC/CBI) is a new interdisciplinary initiative at the University of Texas Health Science Center at San Antonio (UTHSCSA) and the University of Texas at San Antonio (UTSA) which was launched in January 2005. The overall goal of the initiative is to build infrastructure to significantly advance collaborative interdisciplinary bioscience research in San Antonio.
This laboratory houses an impressive collection of high-end microscopes including one of the most powerful transmission electron microscopes in the world. The microscope is kept in a specially designed space that inhibits intrusive vibrations. Its atomic resolution is propelling world-class research in nanotechnology, biology, chemistry, geology, engineering and medicine.
The laboratory's microscopes are accessible to trained collaborators from other institutions.
The mission of the Biophotonics Core is to provide cutting edge technology for the study and manipulation of biological samples using light. A state-of-the-art inverted confocal/multi-photon system by Zeiss, complete with oxygen and temperature control, permits long-term in-depth imaging of live tissues. Our instrumentation also includes technology to probe at the molecular level for protein-protein interactions within live samples. The core partners with the RCMI Computational Systems Biology Core to create a data acquisition and analysis pipeline that ensures a streamlined and seamless workflow for researchers. To ensure that the full potential of core technology is realized, the Biophotonics Core provides personal training in the use of all instrumentation, as well as the latest methods of data analysis.
The objective of the Computational Systems Biology Core facility (CSBC) is to provide computational support for basic and translational health research at UTSA with the following specific aims:
- Build the computational infrastructure to support modeling and simulation of biological systems
- Live cell imaging
- Protein Biomarker research
The Nanotechnology and Human Health Core is part of the RCMI program at UT San Antonio. It focuses on the synthesis and characterization of nanomaterials for imaging, labels for bioassays, and active targeting for in vivo or in vitro diagnostics. The Core studies the interaction of nanoparticles with living cells for application in the targeted delivery of drugs, genes, and proteins; tissue engineering scaffolds; artificial organs and implants; and bioimaging and cell labeling. Additionally, the Core supports development of new advanced characterization methods to study biological tissue using nanoparticles and advanced electron microscopy techniques to produce three-dimensional structural information for imaging cell membranes, organelles, and other subcellular structures.
The RCMI Proteomics & Protein Biomarkers Cores at the University of Texas at San Antonio (UTSA) are focused on capillary liquid chromatography-mass spectrometry (LC/MS) and -tandem mass spectrometry (LC/MS/MS), to identify, characterize, and quantify proteins. The Proteomics Core develops novel methods, while the Protein Biomarkers Core applies these methods to discover and validate novel protein biomarkers of disease. Highly specific and sensitive protein biomarkers offer profound health care benefits for diagnosis and treatment, including understanding and reducing health disparities in minority populations. Moreover, protein biomarkers are promising therapeutic targets for new drugs.The RCMI Program at UTSA is funded by Research Centers in Minority Institutions (RCMI) grants from the National Center for Research Resources (5 G12RR013646-12) and the National Insitute on Minority Health & Health Disparities (NIMHD)(8 G12MD007591-12) from the National Institutes of Health (NIH), UTSA, and generous donations.
The Image Analysis Core provides state-of-the-art techniques and software for making use of 3-dimensional images acquired via the RCMI Advanced Imaging Center. Our existing facility, like other centers of its kind, offers investigators the capability to acquire large, high resolution, three dimensional data sets, often as time series. The Core assists investigators in establishing methods for reducing these complex data sets to a form suitable for statistical analysis.
The Core draws on the computational resources of The Computational Biology Initiative (CBI) at UTSA to implement standard best practices in image analysis and deliver state of the art image storage, visualization, and quantification to users of the image center, or to users obtaining similar images from equipment in their own laboratories.
The mission of The Neurostatistics Core is to promote the use of the most effective and current biostatistical methods among Neuroscience faculty and students, and to make these methods more generally available. It is designed to overcome the communication gap between experimental neuroscientists and statisticians by integrating statistical experts, in the form of Applied Biostatistics PhD students, directly into the laboratories of SNRP Project Investigators.
The X-ray diffraction facility, under the supervision and care of Dr. Hadi Arman, offers the chemistry department with the means of single crystal X-ray diffraction analysis which is the most reliable route for ascertaining the structure of crystalline materials. The facility maintains a state of the art Rigaku diffractometer. This sealed tube system is equipped with a CCD area detector and can analyze samples at various temperatures. The facility also performs data processing, analysis and solution on samples. In addition to the diffractometer, the facility also has access to the electronic Cambridge Structural Database..
Found 11 core laboratories .