-Orthopedic and cardiovascular biomaterials
The research areas at the AIMS lab include biomaterial constructs for both orthopedic and cardiovascular applications of tissue engineering and drug delivery. We are investigating cell interactions in cocultures and in a variety of polymeric scaffolds to develop biodegradable tissue engineering scaffolds for bone regeneration and angiogenesis in large bone defects. Tissue engineering approaches are also being employed to develop an in vivo coronary artery occlusion model as well as to improve treatment for aortic aneurysms. In the area of drug delivery, we are investigating the use of self-assembled monolayers to attach drug molecules to the surfaces of metal stents used in coronary arteries and other implants.